Building Transcription Factor Binding Site Models to Understand Gene Regulation in Plants
نویسندگان
چکیده
منابع مشابه
Transcription Factor Binding Site Prediction with Multivariate Gene Expression Data
Multi-sample microarray experiments have become a standard experimental method for studying biological systems. A frequent goal in such studies is to unravel the regulatory relationships between genes. During the last few years, regression models have been proposed for the de novo discovery of cis-acting regulatory sequences using gene expression data. However, when applied to multi-sample expe...
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The common approach to find co-regulated genes is to cluster genes based on gene expression. However, due to the limited information present in any dataset, genes in the same cluster might be co-expressed but not necessarily co-regulated. In this paper, we propose to integrate known transcription factor binding site information and gene expression data into a single clustering scheme. This sche...
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ژورنال
عنوان ژورنال: Molecular Plant
سال: 2019
ISSN: 1674-2052
DOI: 10.1016/j.molp.2018.10.010